Epidemiology

• Involved in Bhopal, India industrial accident

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Etiology

• Pesticide Synthesis

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Physiology

• Methyl Isocyanate Inhalation
  • Respiratory Irritant: no cyanide-mediated mechanism is involved

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Clinical

• Cough (see Cough, [[Cough]])
• Acute Lung Injury-ARDS (see xxxxx, [[Acute Lung Injury-ARDS]])
  • Pathology: diffuse alveolar damage
• Reactive Airway Dysfunction Syndrome (see Reactive Airway Dysfunction Syndrome, [[Reactive Airway Dysfunction Syndrome]])

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Treatment

• Steroids: may be benficial in acute lung injury, but are unproven

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References

• xx