Inhalational Exposure

• Bromine Liquid: usually handled as liquid -> readily vaporizes -> respiratory irritant
  • More irritating than chlorine
  • Approximately 100-fold more irritating than ammmonia
  • Used in chemical synthesis and water purification
• Methyl Bromide Gas (Bromomethane): respiratory irritant and CNS toxin
  • Used as industrial fumigant

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Diagnosis

• Blood/Urine Inorganic Bromide Level: elevated in methyl bromide toxicity

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Clinical

Pulmonary Manifestations

• Respiratory Irritant (see Cough, [[Cough]])
• Acute Lung Injury-ARDS (see Acute Lung Injury-ARDS, [[Acute Lung Injury-ARDS]])

CNS Manifestations

• Confusion
• Seizures (see Seizures, [[Seizures]])
• Persistent Neurologic Deficits: may occur after acute recovery
  • Asthenia
  • Cognitive Impairment
  • Optical atrophy
  • Paresthesias

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References

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