Anticholinergic Intoxication
Anticholinergic Intoxication
- Brompheniramine: high anticholinergic activity
- Carbinoxamine: high anticholinergic activity
- Chlorpheniramine: high anticholinergic activity
- Clemastine: high anticholinergic activity
- Cyproheptadine: high anticholinergic activity
- Dimenhydrinate: high anticholinergic activity
- Diphenhydramine (Benadryl) (see Diphenhydramine): high anticholinergic activity
- Doxylamine: high anticholinergic activity
- Hydroxyzine (Atarax, Vistaril) (see Hydroxyzine): high anticholinergic activity
- Meclizine (Bonine, Bonamine, Antivert, Postafen, Sea Legs, Dramamine) (see Meclizine): high anticholinergic activity
- Triprolidine: high anticholinergic activity
- Cetirizine (Zyrtec) (see Cetirizine): variable anticholinergic activity
- Loratidine (Claritin) (see Loratidine): low anticholinergic activity
- Desloratadine (Clarinex) (see Desloratadine): low anticholinergic activity
- Fexofenadine (Allegra, Axodin) (see Fexofenadine): low anticholinergic activity
- Levocetirizine (Xyzal) (see Levocetirizine): low anticholinergic activity
Anti-Parkinson’s Medications
- Amantadine (Symmetrel, Symadine) (see Amantadine): low anticholinergic activity
- Benztropine (Cogentin) (see Benztropine): high anticholinergic activity
- Bromocriptine (Parlodel, Cycloset, Brotin) (see Bromocriptine): low anticholinergic activity
- Entacapone (Comtan, Stalevo): low anti-cholinergic activity
- Trihexyphenidyl (Artane) (see Trihexyphenidyl): high anticholinergic activity
- Codeine (see Codeine): low anticholinergic activity
- Fentanyl (see Fentanyl): low anticholinergic activity
- Hydrocodone (see Hydrocodone): low anticholinergic activity
- Meperidine (see Meperidine): low anticholinergic activity
- Methadone (see Methadone): low anticholinergic activity
- Morphine (see Morphine): low anticholinergic activity
- Oxycodone (see Oxycodone): low anticholinergic activity
- Tramadol (see Tramadol): low anticholinergic activity
Antimuscarinic Agents
Antimuscarinic Medications for Overactive Bladder
- Darifenacin: high anti-cholinergic activity
- Fesoterodine (Toviaz) (see Fesoterodine): high anticholinergic activity
- Oxybutynin (Ditropan) (see Oxybutynin): high anticholinergic activity
- Solifenacin (Vesicare) (see Solifenacin): high anticholinergic activity
- Tolterodine (Detrol, Detrusitol) (see Tolterodine): high anticholinergic activity
- Trospium: high anticholinergic activity
Antimuscarinic Spasmolytic Medications
- Atropine (see Atropine): high anticholinergic activity
- Clidinium-Chlordiazepoxide: high anticholinergic activity
- Hyoscyamine: high anticholinergic activity
- Glycopyrrolate (Robinul) (see Glycopyrrolate): high anticholinergic activity
- Homatropine: high anticholinergic activity
- Methscopolamine: high anticholinergic activity
- Scopolamine (Hyoscine) (see Scopolamine): high anticholinergic activity
- Propantheline: high anticholinergic activity
Antimuscarinic Inhaled Bronchodilators
- Ipratropium Bromide (see Ipratropium Bromide): high local anticholinergic activity
- Tiotropium (Spiriva) (see Tiotropium): high local anticholinergic activity
Antimuscarinic Ophthlamic Medications (Mydriatic/Cycloplegic)
- Atropine (see Atropine): high local anticholinergic activity
- Cyclopentolate: high local anticholinergic activity
- Homatropine (see Homatropine): high local anticholinergic activity
- Scopolamine (see Scopolamine): high local anticholinergic activity
Cardiovascular Medications
- Disopyramide (Norpace) (see Disopyramide): low anticholinergic activity
Gastrointestinal Medications
Anti-Emetics
- Hydroxyzine (Atarax, Vistaril) (see Hydroxyzine): high anticholinergic activity
- Meclizine (Bonine, Bonamine, Antivert, Postafen, Sea Legs, Dramamine) (see Meclizine, [[Meclizine]]): high anticholinergic activity
- Promethazine (Phenergan) (see Promethazine): high anticholinergic activity
- Scopolamine (see Scopolamine): high anticholinergic activity
- Prochlorperazine (Compazine) (see Prochlorperazine): low anticholinergic activity
Other
Muscle Relaxants
- Orphenazine: high anticholinergic activity
- Tizanidine (xxx) (see Tizanidine): high anticholinergic activity
- Cyclobenzaprine (xxx): variable anticholinergic activity
- Baclofen (xxx) (see Baclofen): low anticholinergic activity
- Methocarbamol (Robaxin) (see Methocarbamol): low anticholinergic activity
Psychotropic/Neurologic Medications
- Chlordiazepoxide (Librium) (see Chlordiazepoxide): low anticholinergic activity
- Clonazepam (Klonopin, Rivotril, Clonotril) (see Clonazepam): low anticholinergic activity
- Temazepam (Restoril, Normison) (see Temazepam): low anticholinergic activity
- Triazolam (Halcion) (see Triazolam): low anticholinergic activity
First-Generation Antipsychotics
- Chlorpromazine (see Chlorpromazine): high anticholinergic effect
- Fluphenazine (see Fluphenazine): high anticholinergic effect
- Haloperidol (Haldol) (see Haloperidol): low anticholinergic effect
- Loxapine (see Loxapine): high anticholinergic effect
- Methotrimeprazine (Levomepromazine): high anticholinergic effect
- Perphenazine: variable anticholinergic effect
- Thioridazine (see Thioridazine): high anticholinergic activity
- Trifluoperazine: high anti-cholinergic activity
Second-Generation Antipsychotics
- Clozapine (Clozaril) (see Clozapine): high anticholinergic activity
- Olanzapine (Zyprexa) (see Olanzapine): variable anticholinergic activity
- Quetiapine (Seroquel) (see Quetiapine): low anticholinergic activity
- Iloperidone: low anticholinergic activity
- Risperidone (Risperdal) (see Risperidone): low anticholinergic activity
- Citalopram (Celexa) (see Citalopram): low anticholinergic activity
- Fluoxetine (Prozac) (see Fluoxetine): low anticholinergic activity
- Fluvoxamine (Luvox) (see Fluvoxamine): low anticholinergic activity
- Paroxetine (Paxil) (see Paroxetine): variable anticholinergic activity
- Amitriptyline (see Amitriptyline): high anticholinergic activity
- Clomipramine (see Clomipramine): high anticholinergic activity
- Desipramine (see Desipramine): high anticholinergic activity
- Doxepin (see Doxepin): high anticholinergic effect
- Imipramine (see Imipramine): high anticholinergic activity
- Nortriptyline (see Nortriptyline): high anticholinergic activity
Other
- Carbamazepine (Tegretol) (see Carbamazepine): low anticholinergic activity
- Lithium (see Lithium): low anticholinergic activity
- Nefazodone (see Nefazodone): low anticholinergic activity
- Oxcarbazepine (see Oxcarbazepine): low anticholinergic activity
- Phenelzine (see Phenelzine): low anticholinergic activity
- Trazodone (see Trazodone): low anticholinergic activity
Plants/Herbs
- Angel’s Trumpet (Brugmansia Species)
- Henbane (Hyoscyamus Niger)
- Jimson Weed (Datura Stramonium)
- Mandrake (Mandragora Officinarum)
- Moonflower (Datura Inoxia)
- Muscarinic Toxic Mushroom Species (see Toxic Mushrooms)
- Clitocybe: particularly implicated
- Inocybe: particularly implicated
- Amanita
- Entoloma
- Mycena
- Nightshade Species (see Nightshade)
- American Nightshade (Solanum Americanum)
- Bittersweet Woody Nightshade (Solanum Dulcamara)
- Black (Common) Nightshade (Solanum Nigrum)
- Deadly Nightshade (Atropa Belladonna)
Diagnosis
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Clinical Manifestations
Cardiovascular Manifestations
Dermatologic Manifestations
Dry Skin
Neurologic Manifestations
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Treatment
References