Epidemiology

• Mean Age of Onset: 70-80 y/o
• Sex: M>F with 2:1 Ratio

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Etiology

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Physiology

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Diagnosis

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Clinical-Diagnostic Criteria

• Age >50
• Rheumatoid Factor (RF)-Negative
• Sudden Onset
• Pitting Edema of Hands

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Clinical Manifestations

Rheumatologic Manifestations

Symmetric Polyarthritis and Synovitis (see Arthritis, [[Arthritis]])

• Involved Joints
  • Ankles
  • Elbows
  • Knees
  • Metacarpophalangeal Joints
  • Proximal Interphalangeal joints
  • Shoulders
  • Wrists
• Acute Pitting Edema of Back of Hands/Feet (see Peripheral Edema, [[Peripheral Edema]])

Other Manifestations

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Treatment

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References

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