Type 4 Renal Tubular Acidosis (RTA)


Etiology

Hypoaldosteronism (see Hypoaldosteronism)

Decreased Aldosterone Synthesis

Aldosterone Resistance


Physiology

Aldosterone Deficiency/Resistance -> Impaired Distal Tubular Ammonium Generation


Diagnosis


Clinical Manifestations

Renal Manifestations

Hyperkalemia (see Hyperkalemia)

Non-Anion Gap Metabolic Acidosis (NAGMA) (see Metabolic Acidosis-Non Anion Gap)

Absence of Sodium-Wasting and Hyponatremia


Treatment


References