Prospective Trial of the Diagnostic Accuracy of Multiorgan Point-of Care (POCUS) Ultrasound, as Compared to Computed Tomography Pulmonary Artery Angiogram in the Diagnosis of Acute Pulmonary Embolism in Critically Ill Patients with Suspected Pulmonary Embolism (PLoS One, 2022) [MEDLINE]: n = 88
42% of Patients Had Acute Pulmonary Embolism
Multivariate Analysis Demonstrated a Relative Risk of Acute Pulmonary Embolism of 2.79 (95% CI: 1.61-4.84) for the Presence of Right Ventricular Dysfunction, of 2.54 (95% CI: 0.89-7.20) for D-Dimer Level >1000 ng/mL, and of 1.69 (95% CI: 1.12-2.63) for the Absence of an Alternative dDiagnosis to Acute Pulmonary Embolism on Lung POCUS or Chest X-Ray
The Combination with the Highest Diagnostic Accuracy for Acute Pulmonary Embolism Included the Following Variables
POCUS Transthoracic Echocardiography with Evidence of Right Ventricular Dysfunction
Lung POCUS or Chest X-Ray without an Alternative Diagnosis to Acute Pulmonary Embolism
Plasma D-Dimer Level >1000 ng/mL
Combining These Three Findings Resulted in an Area Under the Curve of 0.85 (95% CI: 0.77-0.94)
