O-COPD Randomized Trial of Positive Expiratory Pressure Therapy in Chronic Obstructive Pulmonary Disease (Thorax, 2022) [MEDLINE]
n = 122 (61/61 Oscillatory Positive Expiratory Pressure Therapy/Control) were recruited (103 completed the study: 55/48 Oscillatory Positive Expiratory Pressure Therapy/Control)
40% female
17% smokers
FEV1 38 (25-56)% Predicted
Age 62±10 y/o
Use of Oscillatory Positive Expiratory Pressure was Associated with Improvement in Leicester Cough Questionnaire, as Compared to Control; Median 1.03 (95% CI: 0.71 to 2.10; p = 0.03), Functional Assessment of Chronic Illness Therapy Score 4.68 (95% CI: 1.34 to 8.02; p<0.001), and EuroQol-5 Dimensions Score 4.00 (95% CI: 0.49 to 19.75; p=0.04)
There was Also an Improvement in Cough Frequency -60 (-43 to -95) Coughs/24 hours (p<0.001), But No Statistically Significant Effect on Sleep Disturbance was Identified
Regular Use of an Acapella Device Improves Symptoms and Quality of life in COPD Patients Who Produce Sputum Daily or Most Days
Technique
Brands
Acapella
Aerobika
Bottle PEP
PARI O-PEP
Flutter
Turboforte®
Physiology
clearance of excess secretions from the lungs
reducing gas trapping and improving ventilation of the lungs
Adverse Effects
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References
Oscillatory positive expiratory pressure therapy in COPD (O-COPD): a randomised controlled trial. Thorax. 2022 Aug 10;thoraxjnl-2022-219077. doi: 10.1136/thorax-2022-219077 [MEDLINE]