Hypercapnic Respiratory Failure in Setting Acute Chronic Obstructive Pulmonary Disease (COPD) Exacerbation (see Chronic Obstructive Pulmonary Disease)
Clinical Efficacy
Trial of Extracorporeal Carbon Dioxide Removal (as Add-On Therapy to Noninvasive Positive-Pressure Ventilation) in the Treatment of COPD Exacerbation with Hypercapnic Respiratory Failure (Ann Intensive Care, 2022) [MEDLINE]: n = 18
As Compared to Noninvasive Positive-Pressure Ventilation (NIPPV) Alone, Noninvasive Ventilation and ECCO2R Resulted in Increased ICU and Hospital Length of Stay with No Difference in 90-Day Mortality or Functional Outcomes
Adverse Effects/Complications
Hematologic Adverse Effects/Complications
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References
A randomised controlled trial of non-invasive ventilation compared with extracorporeal carbon dioxide removal for acute hypercapnic exacerbations of chronic obstructive pulmonary disease. Ann Intensive Care. 2022 Apr 21;12(1):36. doi: 10.1186/s13613-022-01006-8 [MEDLINE]
