Epidemiology

• Used to treat glioblastoma and metastatic melanoma

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Pharmacology

• Alkylating agent

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Adverse Effects

• Pneumonitis (see [[Pneumonia]]): occurs in 4.8% of cases
• Cryptogenic Organizing Pneumonia (see [[Cryptogenic Organizing Pneumonia]]): one case report
  • Resolved with discontinuation of drug
• Pharyngitis
• Sinusitis
• Cough
• Upper Respiratory Tract Infection
• Dyspnea

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References

• xxx