Indications

• Hyperphosphatemia (see Hyperphosphatemia, [[Hyperphosphatemia]])

---

Contraindications

• Hypophosphatemia (see Hypophosphatemia, [[Hypophosphatemia]])
• Bowel Obstruction

---

Pharmacology

• Phosphate Binder (see Phosphate Binders, [[Phosphate Binders]]): when taken with meals, sevelamer binds to dietary phosphate and prevents intestinal absorption

---

Administration

• PO:

---

Adverse Effects

Cardiovascular Adverse Effects

• Hypertension (see Hypertension, [[Hypertension]])
• Hypotension (see Hypotension, [[Hypotension]])

Gastrointestinal Adverse Effects

• Constipation (see Constipation, [[Constipation]])
• Dyspepsia
• Diarrhea (see Diarrhea, [[Diarrhea]])
• Flatulence
• Nausea/Vomiting (see Nausea and Vomiting, [[Nausea and Vomiting]])

---

References

• xxxx