Indications

• Congestive Heart Failure (CHF) (see Congestive Heart Failure, [[Congestive Heart Failure]])

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Pharmacology

• Sacubitril: neprilysin inhibitor
• Valsartan (see Valsartan, [[Valsartan]]): angiotensin II receptor blockers (ARB)

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Administration

• xxxx

Dose Adjustment

• Hepatic:
• Renal:

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Adverse Effects

Allergic/Immunologic Adverse Effects

Angioedema (see Urticaria-Angioedema, [[Urticaria-Angioedema]])

• Epidemiology
  • Angioedema is associated with both sacubitril and valsartan

Other Adverse Effects

• xxx
• xxx
• xxx

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References

• xxxx