Norepinephrine (Levophed)
Indications
Pharmacology
- α1-Adrenergic Receptor Agonist (see α1-Adrenergic Receptor Agonists, [[α1-Adrenergic Receptor Agonists]])
- β1-Adrenergic Receptor Agonist (see β1-Adrenergic Receptor Agonists, [[β1-Adrenergic Receptor Agonists]])
- Positive Chronotropy with Increase in Blood Pressure) -> increased cardiac output
- Positive Inotropy (with Increase in Blood Pressure) -> increased cardiac output
- β2-Adrenergic Receptor Agonist (see β2-Adrenergic Receptor Agonists, [[β2-Adrenergic Receptor Agonists]])
- xxx
Metabolism
Administration
Dose Adjustment
Risk of Extravasation-Associated Tissue Damage
Adverse Effects
Cardiovascular Adverse Effects
- Arrhythmias
- Exacerbation of Myocardial Ischemia (see Coronary Artery Disease, [[Coronary Artery Disease]])
- Hypertension (see Hypertension, [[Hypertension]]): especially in patients on non-selective beta blockers
- QT Prolongation without Definite Association with Torsade (see Torsade, [[Torsade]])
- Sinus Tachycardia (see Sinus Tachycardia, [[Sinus Tachycardia]])
Other Adverse Effects
References