Indications

• Need for Procedural/Operative Paralysis
• Need for Sedation to Facilitate Mechanical Ventilation in Acute Respiratory Distress Syndrome (ARDS) (see Acute Respiratory Distress Syndrome, [[Acute Respiratory Distress Syndrome]])
• Rapid Sequence Intubation (RSI) (see Airway Management, [[Airway Management]])

Agents

Benzylisoquinolines

• Alcuronium
• Atracurium (Tracrium) (see Atracurium)
• Cisatracurium (Nimbex) (see Cisatracurium)
• Doxacurium (Nuromax))
• Mivacurium
• Tubocurarine

Aminosteroids

• Pancuronium (Pavulon) (see Pancuronium)
• Pipecuronium (Arduan)
• Rapacuronium
• Rocuronium (Zemuron, Esmeron) (see Rocuronium)
• Vecuronium (Norcuron) (see Vecuronium)

Depolarizing

• Succinylcholine (see Succinylcholine)

References

• Clinical practice guidelines for sustained neuromuscular blockade in the adult critically ill patient. Crit Care Med. 2002;30:142-158
• Elimination of atracurium in humans: contribution of Hofmann elimination and ester hydrolysis versus organ-based elimination. Anesthesiology. 1986;65:6-12