Methylphenidate (Ritalin)


  • Abused both in PO and IV (crushed, dissolved) forms


  • Methylphenidate is a dopamine and norepinephrine reuptake inhibitor

Clinical Presentations


  • Panlobular pulmonary emphysema caused by IV injection of methylphenidate (Ritalin): findings on chest radiographs and CT scans. Am J Roentgenol 1994; 162: 555-560
  • Severe precocious emphysema in intravenous methylphenidate (Ritalin) abusers. Chest 1987; 92: 1085-1087
  • Eosinophilic syndrome with methylphenidate abuse. Ann Intern Med 1978; 89: 224-225