Indications

Intensive Care Unit Sedation (see Sedation, [[Sedation]])

• Need for Sedation While on Mechanical Ventilation

Intoxication/Withdrawal

• Ethanol Withdrawal (see Ethanol, [[Ethanol]])

Procedural Sedation (see Sedation, [[Sedation]])

• Bone Marrow Biopsy (see Bone Marrow Biopsy, [[Bone Marrow Biopsy]])
• Bronchoscopy (see Bronchoscopy, [[Bronchoscopy]])
• Cardioversion for Atrial Fibrillation (see Atrial Fibrillation, [[Atrial Fibrillation]])
• Dental Procedures
• Endoscopy
  • Colonoscopy (see Colonoscopy, [[Colonoscopy]])
  • Esophagogastroduodenoscopy (EGD) (see Esophagogastroduodenoscopy, [[Esophagogastroduodenoscopy]])
• Fine Needle Aspiration (FNA) of Mass/Lesion
• Foreign Body Extraction: particularly in pediatric populations
• Surgery

Other

• Anxiety (see Anxiety, [[Anxiety]])
• Insomnia (see Insomnia, [[Insomnia]])

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Pharmacology

• Benzodiazepine (see Benzodiazepines, [[Benzodiazepines]])

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Administration

• PO: 0.5-1 mg PRN
• IV: 0.5-1 mg PRN

Dose Adjustment

• Hepatic
• Renal

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Adverse Effects

Cardiovascular Adverse Effects

Hypotension (see Hypotension, [[Hypotension]])

• xxx

Gastrointestinal Adverse Effects

Increased Risk of Hepatic Encephalopathy (see Hepatic Encephalopathy, [[Hepatic Encephalopathy]])

• xxx

Pulmonary Adverse Effects

Respiratory Depression

• Acute Hypoventilation (see Acute Hypoventilation, [[Acute Hypoventilation]])
• Chronic Hypoventilation (see Chronic Hypoventilation, [[Chronic Hypoventilation]])

Toxicologic Adverse Effects

Propylene Glycol Intoxication (see Propylene Glycol, [[Propylene Glycol]])

• Epidemiology: associated with continuous intravenous administration

Other Adverse Effects

• xxx
• xxx
• xxx

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References

• xxx