Ketamine


Indications/Exposures

Anesthesia Where Skeletal Muscle Relxation is Not Required

Bipolar Disorder (see Bipolar Disorder, [[Bipolar Disorder]])

Complex Regional Pain Syndrome

Depression (see Depression, [[Depression]])

Drug of Abuse

Intensive Care Unit Sedation (see Sedation, [[Sedation]])

Neuropathic Pain (see xxxx, [[xxxx]])

Post-Operative Analgesia

Procedural Sedation (see Sedation, [[Sedation]])

Refractory Bronchospasm Due to Status Asthmaticus (see Asthma, [[Asthma]])

Sedation in Traumatic Brain Injury (TBI) (see Traumatic Brain Injury, [[Traumatic Brain Injury]])


Contraindications


Pharmacology

Non-Barbiturate Dissociative Anesthetic

Pharmacokinetics (Intravenous)

Metabolism


Administration

Dose Adjustment

Use in Pregnancy (see Pregnancy, [[Pregnancy]])

Use During Lactation

Cautions


Adverse Effects

Allergic Adverse Effects

Cardiovascular Adverse Effects

Gastrointestinal Adverse Effetcs

Neurologic Adverse Effects

Diplopia (see Diplopia, [[Diplopia]])

Emergence Reaction

Fasciculations

Hyporeflexia (see Hyporeflexia, [[Hyporeflexia]])

Increased Cerebrospinal Fluid (CSF) Pressure

Increased Intraocular Pressure

Nystagmus (see Nystagmus, [[Nystagmus]])

Tonic-Clonic Movements (Seizure-Like Movements)

Pulmonary Adverse Effects

Respiratory Depression (see Acute Hypoventilation, [[Acute Hypoventilation]])

Laryngospasm (see Laryngospasm, [[Laryngospasm]])

Renal Adverse Effects

Other Adverse Effects


Ketamine Abuse Syndrome

Clinical Manifestations

Neurologic Manifestations


Ketamine Withdrawal

Epidemiology

Clinical Manifestations

Neurologic Manifestations


References