Ivacaftor


Indications

Cystic Fibrosis with G551D Mutation (in At Least One of Their CFTR Genes) (see Cystic Fibrosis, [[Cystic Fibrosis]])

Cystic Fibrosis with Other CFTR “Gating Mutations” (see Cystic Fibrosis, [[Cystic Fibrosis]])


Pharmacology

Metabolism


Administration

Monitor Liver Function Tests (LFT’s)

Dose Adjustment

Drug Interactions


Adverse Effects

Gastrointestinal Adverse Effects

Ophthlamologic Adverse Effects


References