Pharmacology

• Variation in the N-acetyltransferase gene (NAT2) divides people into “slow acetylators” and “fast acetylators,” with very different half-lives and blood concentrations of important drugs such as isoniazid

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Adverse Effects

Pulmonary Adverse Effects

• Pulmonary Infiltrates with Eosinophilia (see Drug-Induced Pulmonary Eosinophilia)

Hepatic Adverse Effects

• Hepatotoxicity

Rheum Adverse Effects

• Drug-Induced Systemic Lupus Erythematosus (see Systemic Lupus Erythematosus)

Hematologic Adverse Effects

• Sideroblastic Anemia (see Anemia)

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References

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