Indications
- Angiotensin Converting Enzyme (ACE) Inhibitor-Associated Angioedema (see Angiotensin Converting Enzyme Inhibitors, Angiotensin Converting Enzyme Inhibitors)
- Angiotensin II Receptor Blocker (ARB)-Associated Angioedema (see Angiotensin II Receptor Blockers, Angiotensin II Receptor Blockers)
- Hereditary Angioedema (see Angioedema, Angioedema)
Pharmacology
- Synthetic Decapeptide Bradykinin-2 Receptor Antagonist: blocks the vascular effects of bradykinin
Metabolism
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Administration
- SQ: single dose 30 mg
- Second/Third Doses May Occasionally Be Required
Dose Adjustment
- Hepatic:
- Renal:
Adverse Effects
Other Adverse Effects
- Pain/Erythema at Injection Site: occurs in 97% of cases
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References
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