Indications

• Ascites (see Ascites, [[Ascites]])
• Congestive Heart Failure (CHF) (see Congestive Heart Failure, [[Congestive Heart Failure]])
• Edema
  • Cirrhosis
  • Congestive Heart Failure (CHF) (see Congestive Heart Failure, [[Congestive Heart Failure]])
  • Renal Failure: nephrotic syndrome, etc
• Hypertension (see Hypertension, [[Hypertension]])

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Pharmacology

• Sulfonamide Loop Diuretic (see Sulfonamides, [[Sulfonamides]]): inhibition of sodium-potassium-chloride cotransport in the ascending loop of Henle

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Administration

• PO:
• IV:
• IV Drip:

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Adverse Effects

Renal Adverse Effects

• Hypokalemia (see Hypokalemia, [[Hypokalemia]])
• Hypomagnesemia (see Hypomagnesemia, [[Hypomagnesemia]])

GI Adverse Effects

• Acute Pancreatitis (see Acute Pancreatitis, [[Acute Pancreatitis]]): definite association with pancreatitis

Other Adverse Effects

• Ototoxicity/Hearing Loss

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References

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