Indications

• xxx

---

Pharmacology

• Macrolide Antibiotic (see Macrolides, [[Macrolides]])

Metabolism

• xxxx

---

Administration

• PO: xxx

Dose Adjustment

• Hepatic
• Renal

---

Adverse Effects

Cardiovascular Adverse Effects

• Q-T Prolongation with Definite Association with Torsade (see Torsade, [[Torsade]])

Gastrointestinal Adverse Effects

• Elevation of Hepatic Transaminases with Hepatocellular Injury (see Drug-Induced Hepatotoxicity, [[Drug-Induced Hepatotoxicity]])
• Acute Pancreatitis (see Acute Pancreatitis, [[Acute Pancreatitis]]): questionable association

Pulmonary Adverse Effects

• Drug-Induced Pulmonary Eosinophilia (see Drug-Induced Pulmonary Eosinophilia, [[Drug-Induced Pulmonary Eosinophilia]])
  • Epidemiology: has been reported with Azithromycin, Clarithromycin, Erythromycin, and Roxithromycin

Renal Adverse Effects

• Acute Interstitial Nephritis (see Acute Interstitial Nephritis, [[Acute Interstitial Nephritis]])

Other Adverse Effects

• xxx

---

References

• xxx