Indications

• Pneumocystis Jirovecii Prophylaxis (see Pneumocystis Jirovecii, [[Pneumocystis Jirovecii]])
  • Prophylaxis
  • Treatment

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Pharmacology

• xxx

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Administration

• PO

Dose Adjustment

• Hepatic
• Renal

Cautions

• Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency (see Glucose-6-Phosphate Dehydrogenase Deficiency, [[Glucose-6-Phosphate Dehydrogenase Deficiency]]): dapsone should be used with great caution
• Hemoglobin M: dapsone should be used with great caution
• Methemoglobin Reductase Deficiency: dapsone should be used with great caution

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Adverse Effects

Hematologic Adverse Effects

• Risk of Hemolysis in Patient with Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency (see Glucose-6-Phosphate Dehydrogenase Deficiency, [[Glucose-6-Phosphate Dehydrogenase Deficiency]] and Hemolytic Anemia, [[Hemolytic Anemia]])

Pulmonary Adverse Effects

• Drug-Induced Pulmonary Eosinophilia (see Drug-Induced Pulmonary Eosinophilia, [[Drug-Induced Pulmonary Eosinophilia]])
• Drug Rash with Eosinophilia and Systemic Symptoms (DRESS Syndrome) (see Drug Rash with Eosinophilia and Systemic Symptoms, [[Drug Rash with Eosinophilia and Systemic Symptoms]])

Toxicologic Adverse Effects

• Methemoglobinemia (see Methemoglobinemia, [[Methemoglobinemia]])

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References

• xxx