Cephalosporins
Pharmacology
- Semi-Synthetic Beta-Lactam Antibiotics (see β-Lactam Antibiotics, [[β-Lactam Antibiotics]]): derived from Cephalosporium mold
- Inhibition of bacterial cell synthesis (similar to penicillins)
Agents
First Generation
- Cefadroxil (Duricef) (see Cefadroxil, [[Cefadroxil]])
- Cefazolin (Ancef, Kefzol) (see Cefazolin, [[Cefazolin]])
- Cephalexin (Keflex) (see Cephalexin, [[Cephalexin]])
- Cephradrine (Velosef) (see Cephradrine, [[Cephradrine]])
Second Generation
- Cefaclor (Ceclor, Raniclor) (see Cefaclor, [[Cefaclor]])
- Cefotetan (Cefotan) (see Cefotetan, [[Cefotetan]])
- Cefotiam (see Cefotiam, [[Cefotiam]])
- Cefoxitin (Mefoxin) (see Cefoxitin, [[Cefoxitin]])
- Cefprozil (Cefzil) (see Cefprozil, [[Cefprozil]])
- Cefuroxime (Zinacef, Ceftin) (see Cefuroxime, [[Cefuroxime]])
- Loracarbef (Lorabid) (see Loracarbef, [[Loracarbef]])
Third Generation
- Cefdinir (Omnicef) (see Cefdinir, [[Cefdinir]])
- Cefditoren (Sprectacef) (see Cefditoren, [[Cefditoren]])
- Cefixime (Suprax) (see Cefixime, [[Cefixime]])
- Cefoperazone (Cefobid) (see Cefoperazone, [[Cefoperazone]])
- Cefotaxime (Claforan) (see Cefotaxime, [[Cefotaxime]])
- Cefpodoxime (Vantin) (see Cefpodoxime, [[Cefpodoxime]])
- Ceftazidime (Fortaz, Tazicef, Ceptaz) (see Ceftazidime, [[Ceftazidime]])
- Ceftibuten (Cedax) (see Ceftibuten, [[Ceftibuten]])
- Ceftizoxime (Cefizox) (see Ceftizoxime, [[Ceftizoxime]])
- Ceftriaxone (see Ceftriaxone, [[Ceftriaxone]])
Fourth Generation
- Cefepime (Maxipime) (see Cefepime, [[Cefepime]])
Fifth Generation
- Ceftaroline (Teflaro, Zinfloro) (see Ceftaroline, [[Ceftaroline]])
- Ceftobiprole (Zeftera, Zevtera) (see Ceftobiprole, [[Ceftobiprole]])
Adverse Effects
Pulmonary Adverse Effects
- Drug-Induced Pulmonary Eosinophilia (see Drug-Induced Pulmonary Eosinophilia, [[Drug-Induced Pulmonary Eosinophilia]])
- Epidemiology: has been reported with Cephalexin and Cefotiam
Other Adverse Effects
References
