Belatacept (Nulojix)
Indications
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Pharmacology
Fusion Protein Composed of the Fc Fragment of Human IgG1 Immunoglobulin Linked to Extracellular Domain of CTLA-4
- CTLA-4 is a Molecule Crucial in the Regulation of T-Cell Costimulation
- Therefore, Belatacept Selectively Inhibits T-Cell Activation
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Metabolism
Administration
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Dose Adjustment
Use in Pregnancy (see Pregnancy)
Use During Breast Feeding
Adverse Effects
Other Adverse Effects
References