Baloxavir Marboxil (Xofluza)

Indications

Influenza (see Influenza Virus)

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Pharmacology

Influenza Virus CAP-Dependent Endonuclease Inhibitor

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Metabolism

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Administration

Dose

  • xxxx

Dose Adjustment

  • Hepatic:
  • Renal:

Use in Pregnancy (see Pregnancy)

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Use During Breast Feeding

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Adverse Effects

Other Adverse Effects

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References

  • Baloxavir Marboxil for Uncomplicated Influenza in Adults and Adolescents. N Engl J Med 2018; 379:913 [MEDLINE]
  • A Step Forward in the Treatment of Influenza. N Engl J Med. 2018 Sep 6;379(10):975-977. doi: 10.1056/NEJMe1810815 [MEDLINE]
  • Roche media release. Phase III CAPSTONE-2 study showed that baloxavir marboxil reduced symptoms in people at high risk of complications from the flu. https://www.roche.com/media/releases/med-cor-2018-07-17.htm (Accessed on September 08, 2018)
  • Baloxavir: First Global Approval. Drugs 2018; 78:693