MD Nexus
History and Physical Examination
Apremilast (Otezla)
Indications
Psoriasis
(see
Psoriasis
, [[Psoriasis]])
Pharmacology
Phosphodiesterase Type 4 Inhibitor (PDE4 Inhibitor)
(see
Phosphodiesterase Type 4 Inhibitors
, [[Phosphodiesterase Type 4 Inhibitors]])
Phosphodiesterase Type 4 is the Predominant cAMP-Metabolizing Enzyme Found in Inflammatory/Immune Cells
: this explains the anti-inflammatory properties of these agents
Metabolism
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Administration
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Dose Adjustment
Hepatic
:
Renal
:
Adverse Effects
Other Adverse Effects
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xxx
xxx
References
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