Anakinra (Kineret)


Adult-Onset Still’s Disease (see Adult-Onset Still’s Disease)

Behcet’s Disease (see xxxx)

Calcium pyrophosphate crystal deposition disease

Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) COVID-19 (Hospitalized Patient) (see Severe Acute Respiratory Syndrome Coronavirus-2)

Cytokine Release Syndrome (see Cytokine Release Syndrome)

Clinical Efficacy

Hemophagocytic Lymphohistiocytosis (HLH) (see Hemophagocytic Lymphohistiocytosis)

Interleukin-1 Receptor Antagonist Deficiency

Familial Mediterranean Fever (FMF) (see xxxx)

Gout (see Gout)

Neonatal-Onset Multisystem Inflammatory Disease (NOMAD)

Pericarditis (Recurrent) (see xxxx)

Rheumatoid Arthritis (RA) (see xxxx)


Interleukin-1 (IL-1) Receptor Atagonist


Intravenous (IV)

Subcutaneous (SQ)

Dose Adjustment

Adverse Effects

Allergic/Immunologic Adverse Effects

Anaphylaxis (see Anaphylaxis)

Angioedema (see Angioedema)

Antibody Development

Hypersensitivity Reaction

Dermatologic Adverse Effects

Injection Site Reaction

Melanoma (see Melanoma)

Pruritus (see Pruritus)


Urticaria (see Urticaria)

Endocrinologic Adverse Effects

Hypercholesterolemia (see xxxx)

Gastrointestinal/Hepatic Adverse Effect

Constipation (see Constipation)

Gastroenteritis (see Gastroenteritis)

Hepatitis/Elevated Liver Function Tests (LFT’s) (see Elevated Liver Function Tests)

Nausea/Vomiting (see Nausea and Vomiting)

Hematologic Adverse Effects

Leukopenia/Neutropenia (see Leukopenia)

Lymphoma/Malignancy (see Lymphoma)

Infectious Adverse Effects

Increased Risk of Infection

Neurologic Adverse Effects

Anxiety (see Anxiety)

Headache (see Headache)

Otolaryngologic Adverse Effects

Nasopharyngitis (see Pharyngitis)

Otitis Media (see Otitis Media)

Sinusitis/Upper Respiratory Tract Infection (see xxxx)

Renal Adverse Effects

Acute Kidney Injury (AKI) (see Acute Kidney Injury)

Hyperkalemia (see Hyperkalemia)

Hypernatremia (see Hypernatremia)

Rheumatologic Adverse Effects

Arthralgias (see Arthralgias)

Other Adverse Effects

Fever (see Fever)

Hypothermia (see Hypothermia)