Alemtuzumab (Campath, MabCampath, Campath-1H, Lemtrada)
Indications
Transplantation
- Acute Lung Transplant Rejection (Acute Cellular Lung Transplant Rejection) (see Acute Lung Transplant Rejection, [[Acute Lung Transplant Rejection]])
- Conditioning for Bone Marrow Transplantation (see Bone Marrow Transplant, [[Bone Marrow Transplant]])
- Conditioning for Renal Transplantation (see Renal Transplant, [[Renal Transplant]])
- Conditioning for Islet Cell Transplantation
Other
Pharmacology
- Anti-CD52 Monoclonal Antibody: binds to CD52 on mature lymphocytes, targeting them for destruction
- However, does not bind to stem cells from which lymphocytes are derived
Metabolism
Administration
Dose Adjustment
Adverse Effects
Other Adverse Effects
References