Proteus Mirabilis


Microbiology

Proteus Mirabilis is a Member of the Proteus Genus (see Proteus)


Physiology

Proteus Antigens Share Homologous Sequences, Which Cross-React with Certain Self-Antigens Normally Present in Synovial Tissues (Clin Exp Rheumatol, 2017) [MEDLINE]


Clinical Manifestations

Cardiovascular Manifestations

Endocarditis (see Endocarditis)

  • Epidemiology
    • Case Report in Patient with Liver Transplant (Proteus Mirabilis was Isolated from Bronchoalveolar Lavage Fluid and from the Explanted Aortic Valve) (BMJ Case Rep, 2019) [MEDLINE]

Gastrointestinal Manifestations

Gastroenteritis (see Acute Gastroenteritis)

  • Epidemiology
    • XXXXX

Otolaryngologic Manifestations

Acute Rhinosinusitis (see Acute Rhinosinusitis)

  • Epidemiology
    • Proteus Mirabilis May Be Associated with Sinusitis in Neurologically-Impaired Children (Otolaryngol Head Neck Surg, 1998) [MEDLINE]
    • Proteus Mirabilis May Be Associated with ICU-Associated Nosocomial Sinusitis (Braz J Otorhinolaryngol, 2011) [MEDLINE]

Chronic Sinusitis (see Chronic Sinusitis)

  • Epidemiology
    • Proteus Mirabilis May Be Associated (J Rhinol, 1997) [MEDLINE]

Pulmonary Manifestations

Airway Complications in Lung Transplant Patients (see Lung Transplant)

  • Epidemiology
    • Proteus Mirabilis Airway Colonization Has Been Associated with Increased Airway Complications Requiring Intervention in Lung Transplant Patients (Transplant Proc, 2020) [MEDLINE]

Lung Abscess (see Lung Abscess)

  • Epidemiology
    • Case Report of Lung Abscess Associated with Proteus Mirabilis (Clin Infect Dis, 1996) [MEDLINE]
    • Case Report of Pediatric Lung Abscess (at Least Partially) Associated with Proteus Mirabilis (J Microbiol Immunol Infect, 2005) [MEDLINE]

Pneumonia (see Community-Acquired Pneumonia and Hospital-Acquired Pneumonia and Ventilator-Associated Pneumonia)

  • Epidemiology
    • Hospital-Acquired Proteus Mirabilis Pneumonia Cases May Occur (Although Less Commonly Than Other Microbiologic Etiologies of HAP/VAP) (Rev Infect Dis, 1985) [MEDLINE] (J Infect Chemother, 2010) [MEDLINE]
    • Case Report of Proteus Mirabilis Pneumonia in Cystic Fibrosis Patient (Eur J Clin Microbiol Infect Dis, 1990) [MEDLINE]
  • Clinical
    • Pneumatocele Formation Has Been Reported in Some Cases (Postgrad Med J, 1985) [MEDLINE] (Indian J Pediatr, 1987) [MEDLINE]
    • Example: 74 y/o male with history of emphysema, presented with severe community-acquired pneumonia with mucous plugging, bronchoscopy recovered Proteus Mirabilis
  • Treatment
    • Cefepime is Effective (BMC Pharmacol Toxicol, 2016) [MEDLINE]

Renal Manifestations

Urinary Tract Infection (UTI) (see Urinary Tract Infection) (Trends Microbiol, 2017) [MEDLINE]

  • Epidemiology
    • XXXXX

Other Manifestations

  • Bacteremia
    • Epidemiology
      • XXXX
  • Wound Infection

Treatment


References