Invasive Aspergillosis


Risk Factors

Anti-Tumor Necrosis Factor-α (TNFα) Therapy (see Anti-Tumor Necrosis Factor-α Therapy, Anti-Tumor Necrosis Factor-α Therapy)

Chronic Granulomatous Disease (CGD) (see Chronic Granulomatous Disease, Chronic Granulomatous Disease)

Corticosteroids (see Corticosteroids, Corticosteroids)

Extracorporeal Membrane Oxygenation (ECMO) (see Venoarterial Extracorporeal Membrane Oxygenation, Venoarterial Extracorporeal Membrane Oxygenation and Venovenous Extracorporeal Membrane Oxygenation, Venovenous Extracorporeal Membrane Oxygenation)

Hematopoietic Stem Cell Transplant (Bone Marrow Transplant) (see Hematopoietic Stem Cell Transplant, Hematopoietic Stem Cell Transplant)

Impaired Cell-Mediated Immunity (see Immune Defects, Immune Defects)

Influenza Virus Infection (see Influenza Virus, Influenza Virus)

Neutropenia (see Neutropenia, Neutropenia)



Aspergillus (see Aspergillus, Aspergillus)


Inhalation of Aspergillus Conidia into the Airways is Common


Serum Galactomannan (see Serum Galactomannan, Serum Galactomannan)


Recommendations (Infectious Diseases Society of America 2016 Practice Guidelines) (Clin Infect Dis, 2016) [MEDLINE]

Serum (1,3)-β-D-Glucan (see Serum (1–3)-β-D-Glucan, Serum (1-3)-β-D-Glucan)

Recommendations(Infectious Diseases Society of America 2016 Practice Guidelines) (Clin Infect Dis, 2016) [MEDLINE]



Clinical Manifestations

Cardiovascular Manifestations

Endocarditis (see Endocarditis, Endocarditis)

Myocarditis (see Myocarditis, Myocarditis)

Pericarditis (see Acute Pericarditis, Acute Pericarditis)

Dermatologic Manifestations

Cutaneous Aspergillosis

Gastrointestinal Manifestations

General Comments

Abdominal Pain (see Abdominal Pain, Abdominal Pain)

Appendicitis (see Appendicitis, Appendicitis)

Colonic Ulcers (see Colonic Ulcer, Colonic Ulcer)

Gastrointestinal Hemorrhage (see Gastrointestinal Hemorrhage, Gastrointestinal Hemorrhage)

Typhlitis (Neutropenic Enterocolitis) (see Typhlitis, Typhlitis)

Peritonitis (see Peritonitis, Peritonitis)

Neurologic/Ophthalmologic Manifestations

General Comments

Brain Abscess (see Brain Abscess, Brain Abscess)

Endophthalmitis (see Endophthalmitis, Endophthalmitis)

Aspergillus-Related Ischemic Cerebrovascular Accident (CVA) with/without Hemorrhage (see Ischemic Cerebrovascular Accident, Ischemic Cerebrovascular Accident and Intracerebral Hemorrhage, Intracerebral Hemorrhage)

Contiguous Aspergillus Invasion of Central Nervous System From Paranasal Sinuses

Mycotic Aneurysm (Mycotic Aneurysm, Mycotic Aneurysm)

Otolaryngologic Manifestations

Aspergillus Rhinosinusitis

Pulmonary Manifestations

General Comments

Aspergillus Tracheobronchitis

Invasive Pulmonary Aspergillosis