Thrombocytopenia


Etiology

Pseudothrombocytopenia

Impaired Platelet Production

Splenic Platelet Sequestration/Hypersplenism (see Splenomegaly, [[Splenomegaly]])

Abnormal Platelet Distribution/Pooling

Increased Platelet Destruction

Drug/Toxin (see also http://www.ouhsc.edu/platelets/index.html)

Immune Thrombocytopenic Purpura (ITP) (see Immune Thrombocytopenic Purpura, [[Immune Thrombocytopenic Purpura]])

Macroangiopathic Hemolytic Anemia

Microangiopathic Hemolytic Anemia (MAHA) + Thrombocytopenia (see Hemoytic Thrombocytopenic Syndromes)

Other

Unknown/Other Mechanism


Physiology

Normal Platelet Physiology


Diagnosis

Complete Blood Count (CBC) (see Complete Blood Count, [[Complete Blood Count]])

Peripheral Blood Smear (see xxxx, [[xxxx]])


Clinical Locations of Hemorrhage


Clinical Patterns of Bleeding

COAGULOPATHY1


Clinical Manifestations

Hemorrhagic Manifestations


Treatment

Platelet Transfusion (see Platelet Transfusion, [[Platelet Transfusion]])


References