Epidemiology

• xxx

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Physiology

• Heterozygous: no abnormal bleeding (even after surgery)
• Homozygous: delayed bleeding after surgery or trauma
  • Suggests that initial hemostatic response is normal, but that clots were lysed prematurely due to excessive fibrinolysis

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Diagnosis

• xxx

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Clinical Manifestations

Hematologic Manifestations

• Coagulopathy with Hemorrhage (see Coagulopathy, [[Coagulopathy]])
  • Menorrhagia (see xxxx, [[xxxx]])
  • Prolonged Wound Healing

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Treatment

• Epsilon Aminocaproic Acid (Amicar) (see Epsilon Aminocaproic Acid, [[Epsilon Aminocaproic Acid]])
• Tranexamic Acid (see Tranexamic Acid, [[Tranexamic Acid]])

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References

• xxx