Epidemiology

• aka Plasmacytoma

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Physiology

• xxx

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Pathology

• Pathologic Patterns
  • Amyloid deposition: in lung

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Clinical Manifestations

Hematologic Manifestations

• Hypercoagulable State (see Hypercoagulable States, [[Hypercoagulable States]])

Rheumatologic/Orthopedic Manifestations

• Bone Lesions: ribs, clavicles, scapulae
• Metastatic Calcification (see Metastatic Calcification, [[Metastatic Calcification]])

Pulmonary Manifestations

• Single or Multiple Lung Nodules or Masses (see [[Lung Nodule or Mass]])
  • Solitary Plasmacytoma: lobulated nodule with no lobar predilection, calcification, or cavitation
• Pneumonia-Like Infiltrate (see Pneumonia, [[Pneumonia]]): lobar or segmental infiltrate
• Interstitial Infiltrates (see Interstitial Lung Disease-Etiology, [[Interstitial Lung Disease-Etiology]]): rare presentation [J Clin Onc 2010; 28]
• Pleural Effusion (see Pleural Effusion-Exudate, [[Pleural Effusion-Exudate]])

Renal Manifestations

• Acute Kidney Injury (AKI) (see Acute Kidney Injury, [[Acute Kidney Injury]]): due to intratubular deposition and obstruction

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Treatment

• xxx

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References

• xxx