Essential Thrombocythemia (Essential Thrombocytosis)


Hematologic Manifestations

Pulmonary Manifestations

  • Pulmonary Hypertension (see Pulmonary Hypertension): Chronic myeloproliferative disorders can cause pulmonary HTN by various potential mechanisms
    • High cardiac output, auto or surgical asplenia, direct obstruction of pulmonary arteries by circulating megakaryocytes (99), CTEPH (100), portopulmonary HTN, and congestive heart failure may all play a role.


  • Unexplained pulmonary hypertension in chronic myeloproliferative disorders. Chest 2001;120:801-8
  • Pulmonary hypertension secondary to thrombocytosis in a patient with myeloid metaplasia. Chest 1993; 103:642-4