Aplastic Anemia
Etiology
Hereditary
Amegakaryocytic Thrombocytopenia
Down’s Syndrome
Dubowitz Syndrome
Dyskeratosis Congenita
Familial Aplastic Anemia
Fanconi Anemia
Preleukemia : monosomy 7, etc
Reticular Dysgenesis
Seckel Syndrome
Shwachman-Diamond Syndrome
Acquired
Drug
Acetazolamide (Diamox) (see Acetazolamide , [[Acetazolamide]]): moderate risk of aplastic anemia
Acetylsalicylic Acid (Aspirin) (see Acetylsalicylic Acid , [[Acetylsalicylic Acid]])
Allopurinol (see Allopurinol , [[Allopurinol]]): unclear association with aplastic anemia
Bismuth (see Bismuth , [[Bismuth]])
Captopril (Capoten) (see Captopril , [[Captopril]]): low risk of aplastic anemia
Carbamazepine (Tegretol) (see Carbamazepine , [[Carbamazepine]])
Carbimazole (Neo-Mercazole) : unclear association with aplastic anemia
Chloramphenicol (see Chloramphenicol , [[Chloramphenicol]])
Chlordiazepoxide (Librium) : unclear association with aplastic anemia
Chloroquine (see Chloroquine , [[Chloroquine]])
Chlorothiazide (see Chlorothiazide , [[Chlorothiazide]]): low risk of aplastic anemia
Chlorpheniramine
Chlorpromazine (Thorazine, Largactil, Megaphen) (see Chlorpromazine , [[Chlorpromazine]]): unclear association with aplastic anemia
Chemotherapeutic Cytotoxic Drugs : cause bone marrow depression at commonly employed doses
Alkylating Agents
Busulfan (see Busulfan , [[Busulfan]])
Cyclophosphamide (Cytoxan) (see Cyclophosphamide , [[Cyclophosphamide]])
Melphalan (see Melphalan , [[Melphalan]])
Nitrogen Mustard
Antimetabolites
Antimitotics
Cytotoxic Antibiotics
Cimetidine (see Cimetidine , [[Cimetidine]])
Colchicine (see Colchicine , [[Colchicine]])
Dapsone (see Dapsone , [[Dapsone]]): low risk of aplastic anemia
Estrogens : in pregnancy and in high doses in animal studies
Felbamate
Flucytosine (see Flucytosine , [[Flucytosine]]): unclear association with aplastic anemia
Furosemide (Lasix) (see Furosemide , [[Furosemide]]): low risk of aplastic anemia
Gaunidine : unclear association with aplastic anemia
Gold (see Gold , [[Gold]])
Ibuprofen (see Ibuprofen , [[Ibuprofen]])
Indomethacin (Indocin) (see Indomethacin , [[Indomethacin]])
Lithium (see Lithium , [[Lithium]]): unclear association with aplastic anemia
Mepacrine
Mebendazole : unclear association with aplastic anemia
Meprobamate : unclear association with aplastic anemia
Methicillin (see Methicillin , [[Methicillin]]): unclear association with aplastic anemia
Methimazole (Tapazole) (see Methimazole , [[Methimazole]]): low risk of aplastic anemia
Methlydopa (see Methlydopa , [[Methlydopa]]): unclear association with aplastic anemia
Methylprylon : unclear association with aplastic anemia
Penicillamine (see Penicillamine , [[Penicillamine]])
Phenacemide
Phenylbutazone (see Phenylbutazone , [[Phenylbutazone]])
Phenytoin (Dilantin) (see Phenytoin , [[Phenytoin]])
Piperacetazine : unclear association with aplastic anemia
Potassium Perchlorate : unclear association with aplastic anemia
Prochlorperazine (Compazine, Stemzine, Buccastem, Stemetil, Phenotil) (see Prochlorperazine , [[Prochlorperazine]]): unclear association with aplastic anemia
Propylthiouracil (PTU) (see Propylthiouracil , [[Propylthiouracil]]): low risk of aplastic anemia
Quinacrine
Quinidine : unclear association with aplastic anemia
Streptomycin : unclear association with aplastic anemia
Sulfamethoxazole-Trimethoprim (Bactrim) (see Sulfamethoxazole-Trimethoprim , [[Sulfamethoxazole-Trimethoprim]]): unclear association with aplastic anemia
Sulfonamides : sulfa antibiotics, methimazole, methylthiouracil, propylthiouracil, tolbutamide, chlorpropamide, acetazolamide, methazolamide
Sulindac (Clinoril) (see Sulindac )
Tetracycline (see Tetracycline , [[Tetracycline]]): unclear association with aplastic anemia
Thiocyanate : unclear association with aplastic anemia
Ticlopidine (Ticlid) (see Ticlopidine , [[Ticlopidine]]): low risk of aplastic anemia
Infection
Toxin
Arsenic (see Arsenic , [[Arsenic]])
Benzene (see Benzene , [[Benzene]]): frequently produces bone marrow depression
Hydrocarbons (see Hydrocarbons , [[Hydrocarbons]]): chlorinated hydrocarbons
Mercury (see Mercury , [[Mercury]])
Organophosphates (see Organophosphates , [[Organophosphates]])
Other
Diagnosis
Clinical
Treatment
References
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