Etiology

Atopic Disease

• Allergic Bronchopulmonary Aspergillosis (ABPA) (see Allergic Bronchopulmonary Aspergillosis): see below
• Allergic Fungal Sinusitis
• Allergic Rhinitis (see Allergic Rhinitis)
• Asthma (see Asthma): see below
• Atopic Dermatitis (see Atopic Dermatitis)

Immunodeficiency

• Atypical Complete DiGeorge Syndrome
• Hyper IgE-Recurrent Infection Syndrome (Job’s Syndrome, Buckley-Job Syndrome) (see Hyper IgE-Recurrent Infection Syndrome)
• Immune Dysregulation, Polyendocrinopathy, Enteropathy, X-Linked Syndrome (IPEX)
• Netherton Disease
• Omenn Syndrome
• Wiskott-Aldrich Syndrome

Infectious Disease

• Viral
  • Cytomegalovirus (CMV) (see Cytomegalovirus)
  • Epstein-Barr Virus (EBV) (see Epstein-Barr Virus)
  • Human Immunodeficiency Virus (HIV) (see Human Immunodeficiency Virus)
• Bacterial
  • Tuberculosis (see Tuberculosis)
• Fungal
  • Candida (see Candida)
• Parasitic
  • Ascariasis (see Ascariasis)
    • Microbiology
      • XXXX
  • Schistosomiasis (see Schistosomiasis)
    • Microbiology
      • XXXX
  • Strongyloidiasis (see Strongyloidiasis)
    • Microbiology
      • Strongyloides Stercoralis
    • Clinical
      • Peripheral Eosinophilia (see Peripheral Eosinophilia)
  • Tropical Pulmonary Eosinophilia (see Tropical Pulmonary Eosinophilia)
    • Microbiology
      • Wuchereria Bancrofti
      • Brugia Malayi
      • Brugia Timori
    • Clinical
      • Serum IgE is Usually >10,000 ng/mL (4200 IU/mL)

Inflammatory Disease

• Eosinophilic Granulomatosis with Polyangiitis (Churg-Strauss Syndrome) (see Eosinophilic Granulomatosis with Polyangiitis)
• Kimura Disease

Neoplastic Disease

• Hodgkin’s Disease (see Hodgkin’s Disease)
• IgE Myeloma (see Multiple Myeloma)

Pulmonary Disease

• Allergic Bronchopulmonary Aspergillosis (ABPA) (see Allergic Bronchopulmonary Aspergillosis)
  • Elevated: >1000 IU/mL (International Society for Human and Animal Mycology, ISHAM) (Clin Exp Allergy, 2013) [MEDLINE]
    • Generally Higher in ABPA than in Asthma
    • May Be as High as 25k IU/mL
    • Serum IgE May Decrease (But Does Not Usually Normalize) Following Glucocorticoid Administration
• Asthma (see Asthma)
  • Epidemiology:
  • Clinical: xxx
• Cystic Fibrosis (CF) (see Cystic Fibrosis)
  • Epidemiology: IgE is elevated in 22% of cases
  • Clinical: xxx

Other

• Bullous Pemphigoid (see Bullous Pemphigoid)
• Hematopoietic Stem Cell Transplant (HSCT) (see Hematopoietic Stem Cell Transplant)
• Nephrotic Syndrome (see Nephrotic Syndrome)
• Tobacco Abuse (see Tobacco)

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References

• Allergic bronchopulmonary aspergillosis: review of literature and proposal of new diagnostic and classification criteria. Clin Exp Allergy. 2013;43(8):850 [MEDLINE]