Interferon Gamma-1b (Actimmune)
Indications
- Idiopathic Pulmonary Fibrosis (IPF) (see Idiopathic Pulmonary Fibrosis, [[Idiopathic Pulmonary Fibrosis]]): studies demonstrate no clinical benefit
- Non-Small Lung Cancer (see Lung Cancer, [[Lung Cancer]])
Pharmacology
Administration
Adverse Effects
Pulmonary Adverse Effects
- Acute Lung Injury-ARDS (see Acute Lung Injury-ARDS, [[Acute Lung Injury-ARDS]])
- Epidemiology: case reports with use in IPF
- Treatment/Prognosis: unresponsive to steroids and fatal in 3 cases
- Increased Risk of Radiation Pneumonitis (see Radiation Pneumonitis and Fibrosis, [[Radiation Pneumonitis and Fibrosis]])
- Epidemiology: reported to occur with combination XRT + Interferon Gamma therapy in the treatment of non-small cell lung cancer
Other Adverse Effects
References