Icatibant (Firazyr)

Indications


Pharmacology

  • Synthetic Decapeptide Bradykinin-2 Receptor Antagonist: blocks the vascular effects of bradykinin

Metabolism

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Administration

  • SQ: single dose 30 mg
    • Second/Third Doses May Occasionally Be Required

Dose Adjustment

  • Hepatic:
  • Renal:

Adverse Effects

Other Adverse Effects

  • Pain/Erythema at Injection Site: occurs in 97% of cases
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References

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