Hypoxic-Ischemic Brain Injury


Incidence and Mortality




Head Computed Tomography (Head CT) (see Head Computed Tomography)

Brain Magnetic Resonance Imaging (MRI) (see Brain Magnetic Resonance Imaging)

Electroencephalogram (EEG) (see Electroencephalogram)

Cerebral Performance Category (CPC)

Serum Neuron-Specific Enolase (NSE) and S100 Beta (see Serum Neuron-Specific Enolase)

Somatosensory Evoked Potentials (SSEP) (see Somatosensory Evoked Potentials)

Clinical Manifestations

Neurologic Manifestations

Clinical Patterns

Intracranial Hypertension (see Increased Intracranial Pressure)

Myoclonus (see Myoclonus)

Seizures (see Seizures)

Treatment-Immediate Care

Specific Management Post-Cardiac Arrest

Pre-Hospital Therapeutic Hypothermia (see Therapeutic Hypothermia)

Treatment-First 24 Hours of Hospital Care

Specific Management Post-Cardiac Arrest

Intracranial Pressure Monitoring

Myoclonic Status Epilepticus Management

Seizure Management (see Seizures)

Therapeutic Hypothermia (see Therapeutic Hypothermia)


Neurologic Prognosis Related to the Duration of Cardiopulmonary Resuscitation (CPR)

Neurologic Prognosis Related to Clinical Findings (JAMA, 2004) [MEDLINE]

Neurologic Prognostication Guidelines (2015 American Heart Association Guidelines Update for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care) [MEDLINE]

Neurologic Prognosis in Post-Anoxic Vegetative State in Subacute Setting



Seizure Management

Therapeutic Hypothermia