Spironolactone (Aldactone)


Indications

Acne Vulgaris (see Acne Vulgaris)

Clinical Efficacy

Ascites (see Ascites)

Clinical Eficacy

Congestive Heart Failure (CHF) (see Congestive Heart Failure)

Clinical Efficacy

Diuretic-Induced Hypokalemia (see Hypokalemia)

Hirsutism (see Hirsutism)

Hypertension (see Hypertension)

Clinical Efficacy

Peripheral Edema (see Peripheral Edema)

Primary Hyperaldosteronism (see Hyperaldosteronism)


Pharmacology

Aldosterone Receptor Antagonist


Administration

Dose Adjustment

Use in Pregnancy (see Pregnancy)

Use During Breast Feeding

Drug Interactions

Agents Which are Associated with Drug-Induced Hypoaldosteronism (see Hypoaldosteronism)


Adverse Effects

Cardiovascular Adverse Effects

Hypotension (see Hypotension)

Endocrinologic Adverse Effects

Gynecomastia (see Gynecomastia)

Hematologic/Oncologic Adverse Effects

Tumorigenic (in Chronic Use Studies in Rats)

Renal Adverse Effects

Hyponatremia (see Hyponatremia)

Hyperkalemia (see Hyperkalemia)


References