Epidemiology

• Very rare

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Physiology

• Primary malignant lung neoplasm arising from any mesenchymal structure in the lung
• Diagnosis of primary lung sarcoma requires exclusion of sarcoma elsewhere (exclude osteosarcoma with bone scan, exclude otehr types with CT scans)

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Diagnosis

• FOB: TBB usually diagnostic
  -Special stains/ EM may be useful

CXR/Chest CT Pattern:
1) Solitary lung mass
2) Pleural effusion
3) Airway lesion

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Clinical

• See also Obstructive Lung Disease
  Symptoms/ signs:
  -Obstructive symptoms/ signs: when present in or near airway
  -Fever: uncommon

Complications: PE (associated with pulmonary vascular sarcomas)/ pulm-onary osteoarthropathy (uncommon)/ hypoglycemia (uncommon)

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Treatment

Small, well-differentiated type: surgery may be curative

Poorly-differen-tiated type: less curative

Unresectable/recurrent sarcoma: chemo/ XRT are used but survival is usually <1 year

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Prognosis

• Prognosis: survival varies with histologic grade (usually 5-25%)

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