Indications
- Need for Procedural/Operative Paralysis
- Rapid Sequence Intubation (RSI) (see Airway Management, Airway Management)
Pharmacology
- Aminosteroid Neuromuscular Junction Antagonist (see Neuromuscular Junction Antagonists, Neuromuscular Junction Antagonists)
- Mild Vagolytic Effect (at High Doses)
- Absence of Sympathomimetic Effect
Metabolism
- Hepatic: excreted in bile
Administration
- IV (Load/Intubation): 0.6 mg kg
- Onset: 75 sec
- Duration of Action: 33 min
Dose Adjustment
- Hepatic:
- Renal:
Reversal of Neuromuscular Blockade
- Sugammadex (Bridion) (see Sugammadex, Sugammadex)
Adverse Effects
Allergic/Immunologic Adverse Effects
Anaphylactoid Reaction (see Anaphylaxis, Anaphylaxis)
- Epidemiology: more common than with pancuronium/vecuronium
Other Adverse Effects
- xxx
- xxx
- xxx
References
- xxxx