Indications

• Renal Cell Carcinoma (see Renal Cancer)
• Soft Tissue Sarcomas

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Pharmacology

• Tyrosine Kinase Inhibitor

Metabolism

• xxx

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Administration

• xxxx

Dose Adjustment

• Hepatic:
• Renal:

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Adverse Effects

Cardiovascular Adverse Effects

• QT Prolongation without Definite Association with Torsade (see Torsade)
  • xxx
• Hypertension (see Hypertension)
  • xxx

Dermatologic Adverse Effects

• Chemotherapy-Induced Acral Erythema (Hand-Foot Syndrome, Palmar-Plantar Erythrodysesthesia) (see Chemotherapy-Induced Acral Erythema)

Neurologic Adverse Effects

• Posterior Reversible Encephalopathy Syndrome (PRES) (see Posterior Reversible Encephalopathy Syndrome)

Other Adverse Effects

• xxx
• xxx
• xxx

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References

• xxxx