Indications
Pharmacology
- H2-Histamine Receptor Antagonist (see H2-Histamine Receptor Antagonists, [[H2-Histamine Receptor Antagonists]]
- Epithelial Sodium Channel (ENaC) Antagonist (see Epithelial Sodium Channel Antagonists, [[Epithelial Sodium Channel Antagonists]]): acts to close sodium channels on the luminal membrane of cells in the collecting tubule (collecting tubule is the site of action of aldosterone)
Metabolism
Administration
Dose Adjustment
Adverse Effects
Gastrointestinal Adverse Effects
- Acute Pancreatitis (see Acute Pancreatitis, [[Acute Pancreatitis]])
- Epidemiology: probable association
Other Adverse Effects
References