Mycoplasma Pneumoniae


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  • Mycoplasma pneumoniae infection

Physiologic Patterns

  • Diffuse alveolar damage (DAD):
  • Organizing pneumonia: may be seen with DAD


Sputum GS/Cult+Sens:

Pleural fluid: exudate
-Cell count/diff: PMN-predominant

CXR/Chest CT Pattern:
1) Infiltrates:
2) Pleural effusion:
-May occur in up to 20% of cases
-Usually small

Clinical Presentation

Upper Airway Manifestations

  • Pharyngitis
  • Otitis Media
  • Bullous Myringitis
    • Occured in 25% experimental cases from 1960’s studies
    • Occurs in 18% of naturally-occurring cases

Pulmonary Manifestations

  • Pneumonia (see Pneumonia, [[Pneumonia]])
    • Dyspnea
    • Cough
  • Chronic Stable Asthma (see Asthma, [[Asthma]]): Chlamydophila pneumoniae has been found in airways of patients with chronic stable asthma and associated with increased airway inflamation and more severe asthma phenotype
  • Pleural Effusion (see Pleural Effusion-Exudate, [[Pleural Effusion-Exudate]])
  • Acute Lung Injury-ARDS (see Acute Lung Injury-ARDS, [[Acute Lung Injury-ARDS]])

Dermatologic Manifestations


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