Cocaine


Epidemiology


Routes of Cocaine Exposure


Pharmacology

History

Absorption

Mechanisms of Action


Chronic Cocaine Abuse

Epidemiology

Clinical Manifestations

Cardiovascular Manifestations

Infectious Manifestations

Neurologic Manifestations

Otolaryngologic Manifestations

Pulmonary Manifestations

Manifestations Associated with Cocaine Use During Pregnancy (see Pregnancy, [[Pregnancy]])

Other Manifestations

Treatment


Cocaine Intoxication

Diagnosis

Urine Testing for Benzoylecgonine (Main Urinary Metabolite of Cocaine)

Clinical Manifestations

Cardiovascular Manifestations

Dermatologic Manifestations

Gastrointestinal Manifestations

Hematologic Manifestations

Neurologic/Psychiatric Manifestations

Ophthalmologic Manifestations

Pulmonary Manifestations

Acute Respiratory Distress Syndrome (ARDS) (see Acute Respiratory Distress Syndrome, [[Acute Respiratory Distress Syndrome]])
Angioedema (see Angioedema, [[Angioedema]])
Aspiration Pneumonia (see Aspiration Pneumonia, [[Aspiration Pneumonia]])
Asthma Exacerbation (see Asthma, [[Asthma]])
Barotrauma
Cough (see Cough, [[Cough]])
“Crack Lung” (Hemorrhagic Alveolitis)
Cryptogenic Organizing Pneumonia (COP) (see Cryptogenic Organizing Pneumonia, [[Cryptogenic Organizing Pneumonia]])
Diffuse Alveolar Hemorrhage (DAH) (see Diffuse Alveolar Hemorrhage, [[Diffuse Alveolar Hemorrhage]])
Dyspnea (see Dyspnea, [[Dyspnea]])
Lung Mass with/without Cavitation (see Lung Nodule or Mass, [[Lung Nodule or Mass]])
Pharyngeal Burns
Pulmonary Infarction (Am J Med, 1991) [MEDLINE]
Thermal Airway Injury

Renal Manifestations

Rheumatologic Manifestations

Toxicologic Manifestations

Manifestations Associated with Cocaine Use During Pregnancy

Manifestations Related to Cocaine Adulterants

Levamisole (see Levamisole, [[Levamisole]])
Clenbuterol (see Clenbuterol, [[Clenbuterol]])

Treatment

Supportive Care

Treatment of Cocaine Intoxication Associated with Body Packing/Body Stuffing

Treatment of Chest Pain/Acute Myocardial Ischemia or Infarction (see Coronary Artery Disease, [[Coronary Artery Disease]])

Treatment of Ventricular Arrhythmias

Treatment of Agitation (see Agitation, [[Agitation]])

Treatment of Hyperthermia (see Fever, [[Fever]])

Treatment of Hypertension (see Hypertension, [[Hypertension]])

Treatment of Hypotension (see Hypotension, [[Hypotension]])

Treatment of QRS Prolongation


Cocaine Withdrawal

Clinical Manifestations

General Comments

Cardiovascular Manifestations

Neurologic/Psychiatric Manifestations

Gastrointestinal Manifestations

Treatment


References